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Increased platelet storage time is associated with mitochondrial dysfunction and impaired platelet function

BACKGROUND: Hemorrhagic shock is a leading cause of death following severe trauma and platelet transfusions are frequently necessary to achieve hemostasis. Platelets, however, require special storage conditions and storage time has been associated with loss of platelet quality. We hypothesized that...

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Detalhes bibliográficos
Main Authors: Villarroel, José Paul Perales, Figueredo, Ronald, Guan, Yuxia, Tomaiuolo, Maurizio, Karamercan, Mehmet A., Welsh, John, Selak, Mary A., Becker, Lance B., Sims, Carrie
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879371/
https://ncbi.nlm.nih.gov/pubmed/23830370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2013.05.097
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