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Increased platelet storage time is associated with mitochondrial dysfunction and impaired platelet function

BACKGROUND: Hemorrhagic shock is a leading cause of death following severe trauma and platelet transfusions are frequently necessary to achieve hemostasis. Platelets, however, require special storage conditions and storage time has been associated with loss of platelet quality. We hypothesized that...

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Autori principali: Villarroel, José Paul Perales, Figueredo, Ronald, Guan, Yuxia, Tomaiuolo, Maurizio, Karamercan, Mehmet A., Welsh, John, Selak, Mary A., Becker, Lance B., Sims, Carrie
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879371/
https://ncbi.nlm.nih.gov/pubmed/23830370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2013.05.097
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