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Antagonistic Interplay between Necdin and Bmi1 Controls Proliferation of Neural Precursor Cells in the Embryonic Mouse Neocortex

Neural precursor cells (NPCs) in the neocortex exhibit a high proliferation capacity during early embryonic development and give rise to cortical projection neurons after maturation. Necdin, a mammal-specific MAGE (melanoma antigen) family protein that possesses anti-mitotic and pro-survival activit...

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Detalhes bibliográficos
Main Authors: Minamide, Ryohei, Fujiwara, Kazushiro, Hasegawa, Koichi, Yoshikawa, Kazuaki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879318/
https://ncbi.nlm.nih.gov/pubmed/24392139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084460
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