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Subtle Changes in Motif Positioning Cause Tissue-Specific Effects on Robustness of an Enhancer's Activity

Deciphering the specific contribution of individual motifs within cis-regulatory modules (CRMs) is crucial to understanding how gene expression is regulated and how this process is affected by sequence variation. But despite vast improvements in the ability to identify where transcription factors (T...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Erceg, Jelena, Saunders, Timothy E., Girardot, Charles, Devos, Damien P., Hufnagel, Lars, Furlong, Eileen E. M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879207/
https://ncbi.nlm.nih.gov/pubmed/24391522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004060
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