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Coordinated repression and activation of two transcriptional programs stabilizes cell fate during myogenesis

Molecular models of cell fate specification typically focus on the activation of specific lineage programs. However, the concurrent repression of unwanted transcriptional networks is also essential to stabilize certain cellular identities, as shown in a number of diverse systems and phyla. Here, we...

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Detalhes bibliográficos
Main Authors: Ciglar, Lucia, Girardot, Charles, Wilczyński, Bartek, Braun, Martina, Furlong, Eileen E. M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146391/
https://ncbi.nlm.nih.gov/pubmed/24961800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.101956
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