In Vitro and In Vivo Characterization of Helicobacter hepaticus Cytolethal Distending Toxin Mutants

Helicobacter hepaticus expresses a member of the cytolethal distending toxin (CDT) family of bacterial cytotoxins. To investigate the role of CDT in the pathogenesis of H. hepaticus, transposon mutagenesis was used to generate a series of isogenic mutants in and around the cdtABC gene cluster. An H....

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Autori principali: Young, Vincent B., Knox, Kimberly A., Pratt, Jason S., Cortez, Jennifer S., Mansfield, Linda S., Rogers, Arlin B., Fox, James G., Schauer, David B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Bacterial Infections
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC387909/
https://ncbi.nlm.nih.gov/pubmed/15102759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.5.2521-2527.2004
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