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Modulation of Host Immune Responses by the Cytolethal Distending Toxin of Helicobacter hepaticus

Persistent murine infection with Helicobacter hepaticus leads to chronic gastrointestinal inflammation and neoplasia in susceptible strains. To determine the role of the virulence factor cytolethal distending toxin (CDT) in the pathogenesis of this organism, interleukin-10-deficient (IL-10(−/−)) mic...

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Detalhes bibliográficos
Main Authors: Pratt, Jason S., Sachen, Kacey L., Wood, Heather D., Eaton, Kathryn A., Young, Vincent B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1539592/
https://ncbi.nlm.nih.gov/pubmed/16861635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00503-06
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