Modulation of Host Immune Responses by the Cytolethal Distending Toxin of Helicobacter hepaticus

Persistent murine infection with Helicobacter hepaticus leads to chronic gastrointestinal inflammation and neoplasia in susceptible strains. To determine the role of the virulence factor cytolethal distending toxin (CDT) in the pathogenesis of this organism, interleukin-10-deficient (IL-10(−/−)) mic...

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Main Authors: Pratt, Jason S., Sachen, Kacey L., Wood, Heather D., Eaton, Kathryn A., Young, Vincent B.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2006
Teme:
Bacterial Infections
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1539592/
https://ncbi.nlm.nih.gov/pubmed/16861635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00503-06
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