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Contribution of Helicobacter hepaticus Cytolethal Distending Toxin Subunits to Human Epithelial Cell Cycle Arrest and Apoptotic Death in vitro

BACKGROUND: Cytolethal distending toxin (CDT) is the only known virulence factor found in H. hepaticus, the cause of chronic typhlocolitis and hepatitis leading to colonic and hepatocellular carcinomas in mice. Interaction of the tripartite polypeptide CdtA, CdtB and CdtC subunits produced by H. hep...

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Bibliografische gegevens
Hoofdauteurs: Liyanage, Namal P.M., Dassanayake, Rohana P., Kuszynski, Charles A., Duhamel, Gerald E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808484/
https://ncbi.nlm.nih.gov/pubmed/23895367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/hel.12084
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