The effects of Eculizumab on the pathology of malignant atrophic papulosis

BACKGROUND: Degos disease is a frequently fatal and incurable occlusive vasculopathy most commonly affecting the skin, gastrointestinal tract and brain. Vascular C5b-9 deposition and a type I interferon (IFN) rich microenvironment are held to be pathogenetically important in the evolution of the vas...

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Detalhes bibliográficos
Main Authors: Magro, Cynthia M, Wang, Xuan, Garrett-Bakelman, Francine, Laurence, Jeffrey, Shapiro, Lee S, DeSancho, Maria T
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879088/
https://ncbi.nlm.nih.gov/pubmed/24279613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1172-8-185
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