DNA capture and next-generation sequencing can recover whole mitochondrial genomes from highly degraded samples for human identification

BACKGROUND: Mitochondrial DNA (mtDNA) typing can be a useful aid for identifying people from compromised samples when nuclear DNA is too damaged, degraded or below detection thresholds for routine short tandem repeat (STR)-based analysis. Standard mtDNA typing, focused on PCR amplicon sequencing of...

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Bibliographische Detailangaben
Hauptverfasser: Templeton, Jennifer E L, Brotherton, Paul M, Llamas, Bastien, Soubrier, Julien, Haak, Wolfgang, Cooper, Alan, Austin, Jeremy J
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Methodology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879034/
https://ncbi.nlm.nih.gov/pubmed/24289217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2041-2223-4-26
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