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DNA capture and next-generation sequencing can recover whole mitochondrial genomes from highly degraded samples for human identification
BACKGROUND: Mitochondrial DNA (mtDNA) typing can be a useful aid for identifying people from compromised samples when nuclear DNA is too damaged, degraded or below detection thresholds for routine short tandem repeat (STR)-based analysis. Standard mtDNA typing, focused on PCR amplicon sequencing of...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3879034/ https://ncbi.nlm.nih.gov/pubmed/24289217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2041-2223-4-26 |
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