Intranasal Immunization with Multivalent Group A Streptococcal Vaccines Protects Mice against Intranasal Challenge Infections

We have previously shown that a hexavalent group A streptococcal M protein-based vaccine evoked bactericidal antibodies after intramuscular injection. In the present study, we show that the hexavalent vaccine formulated with several different mucosal adjuvants and delivered intranasally induced seru...

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Detalhes bibliográficos
Main Authors: Hall, Mary A., Stroop, Steven D., Hu, Mary C., Walls, Michael A., Reddish, Mark A., Burt, David S., Lowell, George H., Dale, James B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC387888/
https://ncbi.nlm.nih.gov/pubmed/15102757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.5.2507-2512.2004
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