A Novel Live Vector Group A Streptococcal emm Type 9 Vaccine Delivered Intranasally Protects Mice against Challenge Infection with emm Type 9 Group A Streptococci

The availability of a protective vaccine against Streptococcus pyogenes (group A Streptococcus [GAS]) is a priority for public health worldwide. Here, we have generated six live vaccine strains, each engineered to express an N-terminal M protein peptide from one of six of the most prevalent emm type...

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Detalhes bibliográficos
Main Authors: Wozniak, Aniela, García, Patricia, Geoffroy, Enrique A., Aguirre, Daniel B., González, Samantha A., Sarno, Victoria A., Dale, James B., Salazar-Echegarai, Francisco J., Vera, Andrea, Bueno, Susan M., Kalergis, Alexis M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178559/
https://ncbi.nlm.nih.gov/pubmed/25056362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00330-14
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