An improved Bacillus subtilis cell factory for producing scyllo-inositol, a promising therapeutic agent for Alzheimer’s disease

BACKGROUND: Bacillus subtilis 168 possesses an efficient pathway to metabolize some of the stereoisomers of inositol, including myo-inositol (MI) and scyllo-inositol (SI). Previously we reported a prototype of a B. subtilis cell factory with modified inositol metabolism that converts MI into SI in t...

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Detalles Bibliográficos
Main Authors: Tanaka, Kosei, Tajima, Shintaro, Takenaka, Shinji, Yoshida, Ken-ichi
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878828/
https://ncbi.nlm.nih.gov/pubmed/24325193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-12-124
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