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A cell factory of Bacillus subtilis engineered for the simple bioconversion of myo-inositol to scyllo-inositol, a potential therapeutic agent for Alzheimer's disease

BACKGROUND: A stereoisomer of inositol, scyllo-inositol, is known as a promising therapeutic agent for Alzheimer's disease, since it prevents the accumulation of beta-amyloid deposits, a hallmark of the disease. However, this compound is relatively rare in nature, whereas another stereoisomer o...

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Bibliografiske detaljer
Main Authors: Yamaoka, Masaru, Osawa, Shin, Morinaga, Tetsuro, Takenaka, Shinji, Yoshida, Ken-ichi
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176187/
https://ncbi.nlm.nih.gov/pubmed/21896210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-10-69
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