Cross-Reactivity of Schistosoma mansoni Cytosolic Superoxide Dismutase, a Protective Vaccine Candidate, with Host Superoxide Dismutase and Identification of Parasite-Specific B Epitopes

Schistosoma mansoni, an intravascular parasite, has evolved a number of immune evasion mechanisms to establish itself in the host, such as antioxidant enzymes. Our laboratory has demonstrated that the highest levels of certain antioxidant enzymes are found in adult worms, which are the least suscept...

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Main Authors: Carvalho-Queiroz, Claudia, Cook, Rosemary, Wang, Ching C., Correa-Oliveira, Rodrigo, Bailey, Nicola A., Egilmez, Nejat K., Mathiowitz, Edith, LoVerde, Philip T.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Fungal and Parasitic Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC387882/
https://ncbi.nlm.nih.gov/pubmed/15102772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.5.2635-2647.2004
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