High epiregulin expression in human U87 glioma cells relies on IRE1α and promotes autocrine growth through EGF receptor

BACKGROUND: Epidermal growth factor (EGF) receptors contribute to the development of malignant glioma. Here we considered the possible implication of the EGFR ligand epiregulin (EREG) in glioma development in relation to the activity of the unfolded protein response (UPR) sensor IRE1α. We also exami...

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Detalhes bibliográficos
Main Authors: Auf, Gregor, Jabouille, Arnaud, Delugin, Maylis, Guérit, Sylvaine, Pineau, Raphael, North, Sophie, Platonova, Natalia, Maitre, Marlène, Favereaux, Alexandre, Vajkoczy, Peter, Seno, Masaharu, Bikfalvi, Andreas, Minchenko, Dmitri, Minchenko, Oleksandr, Moenner, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878670/
https://ncbi.nlm.nih.gov/pubmed/24330607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-597
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