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Base mediated deprotection strategies for trifluoroethyl (TFE) ethers, a new alcohol protecting group

A trifluoroethyl (TFE) ether is specifically introduced as a protecting group in organic chemistry. Its first strategic application and removal in the total synthesis of vinigrol is discussed. Two lithium base mediated deprotection strategies for its removal are presented in this Letter. In one depr...

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Detalhes bibliográficos
Main Authors: Yang, Qingliang, Njardarson, Jon T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878608/
https://ncbi.nlm.nih.gov/pubmed/24391289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2013.10.097
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