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Dynamic Analysis of Gene Expression and Genome-wide Transcription Factor Binding during Lineage Specification of Multipotent Progenitors

We used the paradigmatic GATA-PU.1 axis to explore, at the systems level, dynamic relationships between transcription factor (TF) binding and global gene expression programs as multipotent cells differentiate. We combined global ChIP-seq of GATA1, GATA2, and PU.1 with expression profiling during dif...

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Detalhes bibliográficos
Main Authors: May, Gillian, Soneji, Shamit, Tipping, Alex J., Teles, Jose, McGowan, Simon J., Wu, Mengchu, Guo, Yanping, Fugazza, Cristina, Brown, John, Karlsson, Göran, Pina, Cristina, Olariu, Victor, Taylor, Stephen, Tenen, Daniel G., Peterson, Carsten, Enver, Tariq
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878573/
https://ncbi.nlm.nih.gov/pubmed/24120743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2013.09.003
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