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Transcriptional Regulation of Lineage Commitment - A Stochastic Model of Cell Fate Decisions
Molecular mechanisms employed by individual multipotent cells at the point of lineage commitment remain largely uncharacterized. Current paradigms span from instructive to noise-driven mechanisms. Of considerable interest is also whether commitment involves a limited set of genes or the entire trans...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3749951/ https://ncbi.nlm.nih.gov/pubmed/23990771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003197 |
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