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Transcriptional Regulation of Lineage Commitment - A Stochastic Model of Cell Fate Decisions

Molecular mechanisms employed by individual multipotent cells at the point of lineage commitment remain largely uncharacterized. Current paradigms span from instructive to noise-driven mechanisms. Of considerable interest is also whether commitment involves a limited set of genes or the entire trans...

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Библиографические подробности
Главные авторы: Teles, Jose, Pina, Cristina, Edén, Patrik, Ohlsson, Mattias, Enver, Tariq, Peterson, Carsten
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749951/
https://ncbi.nlm.nih.gov/pubmed/23990771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003197
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