The Alternative Activation Pathway and Complement Component C3 Are Critical for a Protective Immune Response against Pseudomonas aeruginosa in a Murine Model of Pneumonia

Pseudomonas aeruginosa is a leading cause of hospital-acquired pneumonia, and approximately 80% of patients with cystic fibrosis are infected with this bacterium. To investigate the overall role of complement and the complement activation pathways in the host defense against P. aeruginosa pulmonary...

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Bibliographic Details
Main Authors: Mueller-Ortiz, Stacey L., Drouin, Scott M., Wetsel, Rick A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC387850/
https://ncbi.nlm.nih.gov/pubmed/15102802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.5.2899-2906.2004
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