Mycobacteria Inhibit Nitric Oxide Synthase Recruitment to Phagosomes during Macrophage Infection

Inducible nitric oxide synthase (iNOS) is a cytoplasmic protein responsible for the generation of nitric oxide (NO · ) in macrophages. In this work, we hypothesized that the intracellular localization of iNOS is significant for effective delivery of NO ·  to phagosomes containing ingested microorgan...

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Autores principales: Miller, Barbara H., Fratti, Rutilio A., Poschet, Jens F., Timmins, Graham S., Master, Sharon S., Burgos, Marcos, Marletta, Michael A., Deretic, Vojo
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
Host Response and Inflammation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC387846/
https://ncbi.nlm.nih.gov/pubmed/15102799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.5.2872-2878.2004
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