Mycobacteria Inhibit Nitric Oxide Synthase Recruitment to Phagosomes during Macrophage Infection

Inducible nitric oxide synthase (iNOS) is a cytoplasmic protein responsible for the generation of nitric oxide (NO · ) in macrophages. In this work, we hypothesized that the intracellular localization of iNOS is significant for effective delivery of NO ·  to phagosomes containing ingested microorgan...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Miller, Barbara H., Fratti, Rutilio A., Poschet, Jens F., Timmins, Graham S., Master, Sharon S., Burgos, Marcos, Marletta, Michael A., Deretic, Vojo
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2004
Schlagworte:	Host Response and Inflammation
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387846/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15102799/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.5.2872-2878.2004
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