Spatial and temporal aspects and the interplay of Grb14 and protein tyrosine phosphatase-1B on the insulin receptor phosphorylation

BACKGROUND: Growth factor receptor-bound protein 14 (Grb14) is an adapter protein implicated in receptor tyrosine kinase signaling. Grb14 knockout studies highlight both the positive and negative roles of Grb14 in receptor tyrosine kinase signaling, in a tissue specific manner. Retinal cells are pos...

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Bibliographic Details
Main Authors: Rajala, Raju VS, Basavarajappa, Devaraj K, Dighe, Radhika, Rajala, Ammaji
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878334/
https://ncbi.nlm.nih.gov/pubmed/24350791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-11-96
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