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Protein Tyrosine Phosphatase 1B: A Novel Molecular Target for Retinal Degenerative Diseases

Protein tyrosine phosphatase 1B (PTP1B) is considered as a major negative regulator of insulin receptor (IR) signaling. IR signaling in retina has been demonstrated to be neuroprotective. Photoreceptor specific deletion of PTP1B results in enhanced retinal IR-mediated neuroprotection indicating the...

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Detalhes bibliográficos
Main Authors: Basavarajappa, Devaraj K., Gupta, Vivek K., Rajala, Raju V.S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398709/
https://ncbi.nlm.nih.gov/pubmed/22183413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4614-0631-0_106
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