Enhanced response to pulmonary Streptococcus pneumoniae infection is associated with primary ciliary dyskinesia in mice lacking Pcdp1 and Spef2

BACKGROUND: Lower airway abnormalities are common in patients with primary ciliary dyskinesia (PCD), a pediatric syndrome that results from structural or functional defects in motile cilia. Patients can suffer from recurrent bacterial infection in the lung, bronchiectasis, and respiratory distress i...

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Detalhes bibliográficos
Main Authors: McKenzie, Casey W, Klonoski, Joshua M, Maier, Taylor, Trujillo, Glenda, Vitiello, Peter F, Huber, Victor C, Lee, Lance
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878133/
https://ncbi.nlm.nih.gov/pubmed/24360193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2046-2530-2-18
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