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Genetic interaction between central pair apparatus genes CFAP221, CFAP54, and SPEF2 in mouse models of primary ciliary dyskinesia

Primary ciliary dyskinesia (PCD) is a genetically heterogeneous syndrome that results from defects in motile cilia. The ciliary axoneme has a 9 + 2 microtubule structure consisting of nine peripheral doublets surrounding a central pair apparatus (CPA), which plays a critical role in regulating prope...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: McKenzie, Casey W., Lee, Lance
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378221/
https://ncbi.nlm.nih.gov/pubmed/32704025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69359-3
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