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Polymerases Leave Fingerprints: Analysis of the Mutational Spectrum in Escherichia coli rpoB To Assess the Role of Polymerase IV in Spontaneous Mutation

We compared the distribution of mutations in rpoB that lead to rifampin resistance in strains with differing levels of polymerase IV (Pol IV), including strains with deletions of the Pol IV-encoding dinB gene, strains with a chromosomal copy of dinB, strains with the F′128 plasmid, and strains with...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wolff, Erika, Kim, Mandy, Hu, Kaibin, Yang, Hanjing, Miller, Jeffrey H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC387785/
https://ncbi.nlm.nih.gov/pubmed/15090533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.9.2900-2905.2004
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