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TORC2 signaling antagonizes SKN-1 to induce C. elegans mesendodermal embryonic development

The evolutionarily conserved target of rapamycin (TOR) kinase controls fundamental metabolic processes to support cell and tissue growth. TOR functions within the context of two distinct complexes, TORC1 and TORC2. TORC2, with its specific component Rictor, has been recently implicated in aging and...

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Detalhes bibliográficos
Main Authors: Ruf, Vanessa, Holzem, Christina, Peyman, Tobias, Walz, Gerd, Blackwell, T. Keith, Neumann-Haefelin, Elke
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877771/
https://ncbi.nlm.nih.gov/pubmed/23973804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2013.08.011
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