Nucleophosmin Sets a Threshold for p53 Response to UV Radiation

Because activation of p53 can trigger cell cycle arrest and apoptosis, it is necessary for a cell to suppress this activation until it is absolutely required for survival. The mechanisms underlying this important regulatory event are poorly understood. Here we show that nucleophosmin (NPM) acts as a...

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Detalhes bibliográficos
Main Authors: Maiguel, Dony A., Jones, Leslie, Chakravarty, Devulapalli, Yang, Chonglin, Carrier, France
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC387774/
https://ncbi.nlm.nih.gov/pubmed/15082766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.9.3703-3711.2004
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