Relationships between LDH-A, Lactate and Metastases in 4T1 Breast Tumors

PURPOSE: To investigate the relationship between LDH-A expression, lactate concentration, cell metabolism and metastases in murine 4T1 breast tumors. EXPERIMENTAL DESIGN: Inhibition of LDH-A expression and protein levels were achieved in a metastatic breast cancer cell line (4T1) using shRNA technol...

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Main Authors: Rizwan, Asif, Serganova, Inna, Khanin, Raya, Karabeber, Hazem, Ni, Xiaohui, Thakur, Sunitha, Zakian, Kristen L., Blasberg, Ronald, Koutcher, Jason A.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877680/
https://ncbi.nlm.nih.gov/pubmed/23833310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-3300
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