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The H19 Differentially Methylated Region Marks the Parental Origin of a Heterologous Locus without Gametic DNA Methylation

Igf2 and H19 are coordinately regulated imprinted genes physically linked on the distal end of mouse chromosome 7. Genetic analyses demonstrate that the differentially methylated region (DMR) upstream of the H19 gene is necessary for three distinct functions: transcriptional insulation of the matern...

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書誌詳細
主要な著者: Park, Kye-Yoon, Sellars, Elizabeth A., Grinberg, Alexander, Huang, Sing-Ping, Pfeifer, Karl
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC387767/
https://ncbi.nlm.nih.gov/pubmed/15082756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.9.3588-3595.2004
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