The H19 Differentially Methylated Region Marks the Parental Origin of a Heterologous Locus without Gametic DNA Methylation

Igf2 and H19 are coordinately regulated imprinted genes physically linked on the distal end of mouse chromosome 7. Genetic analyses demonstrate that the differentially methylated region (DMR) upstream of the H19 gene is necessary for three distinct functions: transcriptional insulation of the matern...

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Autors principals: Park, Kye-Yoon, Sellars, Elizabeth A., Grinberg, Alexander, Huang, Sing-Ping, Pfeifer, Karl
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Transcriptional Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC387767/
https://ncbi.nlm.nih.gov/pubmed/15082756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.9.3588-3595.2004
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