BaxΔ2 Family Alternative Splicing Salvages Bax Microsatellite-Frameshift Mutations

Mutation or aberrant splicing can interrupt gene expression. Tumor suppressor Bax is one of the susceptible genes prone to microsatellite frameshifting mutations in coding regions. As a result, tumors exhibiting microsatellite instability (MSI) often present a “Bax-negative” phenotype. We previously...

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Detalhes bibliográficos
Main Authors: Haferkamp, Bonnie, Zhang, Honghong, Kissinger, Samuel, Wang, Xin, Lin, Yuting, Schultz, Megan, Xiang, Jialing
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2013
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877669/
https://ncbi.nlm.nih.gov/pubmed/24386510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601913515906
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