miR-16 and miR-26a target checkpoint kinases Wee1 and Chk1 in response to p53 activation by genotoxic stress

The tumour suppressor p53 is a crucial regulator of cell cycle arrest and apoptosis by acting as a transcription factor to regulate a variety of genes. At least in part, this control is exerted by p53 via regulating expression of numerous microRNAs. We identified two abundantly expressed microRNAs,...

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Hlavní autoři: Lezina, L, Purmessur, N, Antonov, A V, Ivanova, T, Karpova, E, Krishan, K, Ivan, M, Aksenova, V, Tentler, D, Garabadgiu, A V, Melino, G, Barlev, N A
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877554/
https://ncbi.nlm.nih.gov/pubmed/24336073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.483
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