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Induction of necrotic cell death by oxidative stress in retinal pigment epithelial cells

Age-related macular degeneration (AMD) is a degenerative disease of the retina and the leading cause of blindness in the elderly. Retinal pigment epithelial (RPE) cell death and the resultant photoreceptor apoptosis are characteristic of late-stage dry AMD, especially geographic atrophy (GA). Althou...

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Detalhes bibliográficos
Main Authors: Hanus, J, Zhang, H, Wang, Z, Liu, Q, Zhou, Q, Wang, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877549/
https://ncbi.nlm.nih.gov/pubmed/24336085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.478
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