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Carotenoid Derived Aldehydes - Induced Oxidative Stress Causes Apoptotic Cell Death in Human Retinal Pigment Epithelial Cells

Carotenoids have been advocated as potential therapeutic agents in treating age-related macular degeneration (AMD). In ocular tissues carotenoids may undergo oxidation and form carotenoid-derived aldehydes (CDA), which would be toxic to tissues. We have investigated the cytotoxic effects of CDA from...

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Detalhes bibliográficos
Main Authors: Kalariya, Nilesh M., Ramana, Kota V., Srivastava, Satish K., van Kuijk, Frederik J.G.M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786271/
https://ncbi.nlm.nih.gov/pubmed/17977529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2007.09.010
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