Caspase-2 promotes cytoskeleton protein degradation during apoptotic cell death

The caspase family of proteases cleaves large number of proteins resulting in major morphological and biochemical changes during apoptosis. Yet, only a few of these proteins have been reported to selectively cleaved by caspase-2. Numerous observations link caspase-2 to the disruption of the cytoskel...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Vakifahmetoglu-Norberg, H, Norberg, E, Perdomo, A B, Olsson, M, Ciccosanti, F, Orrenius, S, Fimia, G M, Piacentini, M, Zhivotovsky, B
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877538/
https://ncbi.nlm.nih.gov/pubmed/24309927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.463
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