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Enhancement of Sleeping Beauty Transposition by CpG Methylation: Possible Role of Heterochromatin Formation
The Sleeping Beauty (SB) transposase is the most active transposase in vertebrate cells, and the SB transposon system has been used as a tool for insertional mutagenesis and gene delivery. Previous studies have indicated that the frequency of chromosomal transposition is considerably higher in mouse...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC387741/ https://ncbi.nlm.nih.gov/pubmed/15082793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.9.4004-4018.2004 |
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