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Enhancement of Sleeping Beauty Transposition by CpG Methylation: Possible Role of Heterochromatin Formation

The Sleeping Beauty (SB) transposase is the most active transposase in vertebrate cells, and the SB transposon system has been used as a tool for insertional mutagenesis and gene delivery. Previous studies have indicated that the frequency of chromosomal transposition is considerably higher in mouse...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Yusa, Kosuke, Takeda, Junji, Horie, Kyoji
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387741/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15082793/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.9.4004-4018.2004
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