Endocytosis of hERG Is Clathrin-Independent and Involves Arf6

The hERG potassium channel is critical for repolarisation of the cardiac action potential. Reduced expression of hERG at the plasma membrane, whether caused by hereditary mutations or drugs, results in long QT syndrome and increases the risk of ventricular arrhythmias. Thus, it is of fundamental imp...

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Bibliographic Details
Main Authors:	Karnik, Rucha, Ludlow, Melanie J., Abuarab, Nada, Smith, Andrew J., Hardy, Matthew E. L., Elliott, David J. S., Sivaprasadarao, Asipu
Format:	Artigo
Language:	Inglês
Published:	Public Library of Science 2013
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3877390/ https://ncbi.nlm.nih.gov/pubmed/24392021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085630
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Endocytosis of hERG Is Clathrin-Independent and Involves Arf6

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