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Endocytosis of hERG Is Clathrin-Independent and Involves Arf6
The hERG potassium channel is critical for repolarisation of the cardiac action potential. Reduced expression of hERG at the plasma membrane, whether caused by hereditary mutations or drugs, results in long QT syndrome and increases the risk of ventricular arrhythmias. Thus, it is of fundamental imp...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3877390/ https://ncbi.nlm.nih.gov/pubmed/24392021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085630 |
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