Effects of Baseline CSF α-Synuclein on Regional Brain Atrophy Rates in Healthy Elders, Mild Cognitive Impairment and Alzheimer’s Disease

BACKGROUND: Cerebrospinal fluid (CSF) α-synuclein is reduced in synucleinopathies, including dementia with Lewy bodies, and some studies have found increased CSF α-synuclein in Alzheimer’s disease (AD). No study has explored effects of CSF α-synuclein on brain atrophy. Here we tested if baseline CSF...

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Main Authors: Mattsson, Niklas, Insel, Philip, Tosun, Duygu, Zhang, Jing, Jack Jr, Clifford R., Galasko, Douglas, Weiner, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877372/
https://ncbi.nlm.nih.gov/pubmed/24392009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085443
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