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The UL12.5 Gene Product of Herpes Simplex Virus Type 1 Exhibits Nuclease and Strand Exchange Activities but Does Not Localize to the Nucleus

The herpes simplex virus type 1 (HSV-1) alkaline nuclease, encoded by the UL12 gene, plays an important role in HSV-1 replication, as a null mutant of UL12 displays a severe growth defect. Although the precise in vivo role of UL12 has not yet been determined, several in vitro activities have been id...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Reuven, Nina Bacher, Antoku, Susumu, Weller, Sandra K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2004
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387724/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15078942/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.9.4599-4608.2004
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