Loss of aPKCλ in Differentiated Neurons Disrupts the Polarity Complex but Does Not Induce Obvious Neuronal Loss or Disorientation in Mouse Brains

Cell polarity plays a critical role in neuronal differentiation during development of the central nervous system (CNS). Recent studies have established the significance of atypical protein kinase C (aPKC) and its interacting partners, which include PAR-3, PAR-6 and Lgl, in regulating cell polarizati...

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Detalhes bibliográficos
Main Authors: Yamanaka, Tomoyuki, Tosaki, Asako, Kurosawa, Masaru, Akimoto, Kazunori, Hirose, Tomonori, Ohno, Shigeo, Hattori, Nobutaka, Nukina, Nobuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877147/
https://ncbi.nlm.nih.gov/pubmed/24391875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084036
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