Hepatitis C Virus Quasispecies Variability Modulates Nonstructural Protein 5A Transcriptional Activation, Pointing to Cellular Compartmentalization of Virus-Host Interactions

Hepatitis C virus (HCV) behaves in infected patients as a complex mixture of genetically distinct but closely related variants referred to as a “quasispecies.” By using quasispecies analysis strategies, we showed that HCV nonstructural protein 5A (NS5A) has a quasispecies distribution in infected hu...

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Autors principals: Pellerin, Muriel, Lopez-Aguirre, Yolanda, Penin, François, Dhumeaux, Daniel, Pawlotsky, Jean-Michel
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Virus-Cell Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC387712/
https://ncbi.nlm.nih.gov/pubmed/15078944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.9.4617-4627.2004
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