Intraepithelial γδ T Cells May Bridge a Gap between Innate Immunity and Acquired Immunity to Herpes Simplex Virus Type 2

Mice depleted of γδ T cells by in vivo administration of anti-TCRγδ monoclonal antibodies showed susceptibility against an intravaginal infection with herpes simplex virus type 2 (HSV-2). The systemic Th1 response was impaired in the γδ T-cell-depleted mice. Mice deficient in the Vδ1 T subset were s...

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Detalhes bibliográficos
Main Authors: Nishimura, Hitoshi, Yajima, Toshiki, Kagimoto, Yoshiko, Ohata, Mutsuhiro, Watase, Taketo, Kishihara, Kenji, Goshima, Fumi, Nishiyama, Yukihiro, Yoshikai, Yasunobu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC387699/
https://ncbi.nlm.nih.gov/pubmed/15078977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.9.4927-4930.2004
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