Overexpression of Interleukin-15 Increases Susceptibility to Lipopolysaccharide-Induced Liver Injury in Mice Primed with Mycobacterium bovis Bacillus Calmette-Guérin

Mice primed with Mycobacterium bovis bacillus Calmette-Guérin (BCG) are highly sensitive to lipopolysaccharide (LPS)-induced liver injury and lethality. We found that interleukin-15 (IL-15) transgenic (Tg) mice primed with BCG were more susceptible to LPS-induced liver injury than non-Tg mice. The n...

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Detalhes bibliográficos
Main Authors: Yajima, Toshiki, Nishimura, Hitoshi, Saito, Kimika, Kuwano, Hiroyuki, Yoshikai, Yasunobu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC427448/
https://ncbi.nlm.nih.gov/pubmed/15213127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.7.3855-3862.2004
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