Strand-Specific RNA Synthesis Determinants in the RNA-Dependent RNA Polymerase of Poliovirus

The viral RNA-dependent RNA polymerase (3D(pol)) is highly conserved between the closely related enteroviruses poliovirus type 1 (PV1) and coxsackievirus B3 (CVB3). In this study, we generated PV1/CVB3 chimeric polymerase sequences in the context of full-length poliovirus transcripts to determine th...

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Detalhes bibliográficos
Main Authors: Cornell, Christopher T., Perera, Rushika, Brunner, Jo Ellen, Semler, Bert L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC387695/
https://ncbi.nlm.nih.gov/pubmed/15078921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.9.4397-4407.2004
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