Integrin αvβ8 Functions as a Receptor for Foot-and-Mouth Disease Virus: Role of the β-Chain Cytodomain in Integrin-Mediated Infection

Field isolates of foot-and-mouth disease virus (FMDV) have been shown to use three αv integrins, αvβ1, αvβ3, and αvβ6, as cellular receptors. Binding to the integrin is mediated by a highly conserved RGD motif located on a surface-exposed loop of VP1. The RGD tripeptide is recognized by several othe...

ver descrição completa

Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Jackson, Terry, Clark, Stuart, Berryman, Stephen, Burman, Alison, Cambier, Stephanie, Mu, Dezhi, Nishimura, Stephen, King, Andrew M. Q.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2004
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387692/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15078934/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.9.4533-4540.2004
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!