Alcohol-Induced Liver Injury Is Modulated by Nlrp3 and Nlrc4 Inflammasomes in Mice

Alcoholic liver disease (ALD) is characterized by increased hepatic lipid accumulation (steatosis) and inflammation with increased expression of proinflammatory cytokines. Two of these cytokines, interleukin-1β (IL-1β) and IL-18, require activation of caspase-1 via members of the NOD-like receptor (...

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Detalhes bibliográficos
Main Authors: DeSantis, David A., Ko, Chih-wei, Liu, Yang, Liu, Xiuli, Hise, Amy G., Nunez, Gabriel, Croniger, Colleen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876912/
https://ncbi.nlm.nih.gov/pubmed/24453428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/751374
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